Selected Publications: 20-25 publications listed in details with all the contributing authors, title of the papers, journal, dates.


  1. Mantovani A*, Marchesi F*, Malesci A, Laghi L, Allavena P*. Tumor-associated macrophages as treatment targets in oncology. Nat Rev Clin Oncol 2017 14(7):399-416. * equally contributing.


2: Belgiovine C, Bello E, Liguori M, Craparotta I, Mannarino L, Paracchini L,

Beltrame L, Marchini S, Galmarini CM, Mantovani A, Frapolli R, Allavena P,

D’Incalci M. Lurbinectedin reduces tumour-associated macrophages and the

inflammatory tumour microenvironment in preclinical models. Br J Cancer. 2017 Aug

22;117(5):628-638. doi: 10.1038/bjc.2017.205. Epub 2017 Jul 6. PubMed PMID:

28683469; PubMed Central PMCID: PMC5572168.


3: Andon FT, Digifico E, Maeda A, Erreni M, Mantovani A, Alonso MJ, Allavena P.

Targeting tumor associated macrophages: The new challenge for nanomedicine. Semin

Immunol. 2017 Dec;34:103-113. doi: 10.1016/j.smim.2017.09.004. Epub 2017 Sep 21.

Review. PubMed PMID: 28941641.



4: Siddiqui I, Erreni M, Kamal MA, Porta C, Marchesi F, Pesce S, Pasqualini F,

Schiarea S, Chiabrando C, Mantovani A, Allavena P. Differential role of

Interleukin-1 and Interleukin-6 in K-Ras-driven pancreatic carcinoma undergoing

mesenchymal transition. Oncoimmunology. 2017 Nov 1;7(2):e1388485. doi:

10.1080/2162402X.2017.1388485. eCollection 2018. PubMed PMID: 29308316; PubMed

Central PMCID: PMC5749654.


5: Marelli G, Erreni M, Anselmo A, Taverniti V, Guglielmetti S, Mantovani A,

Allavena P. Heme-oxygenase-1 Production by Intestinal CX3CR1(+) Macrophages Helps

to Resolve Inflammation and Prevents Carcinogenesis. Cancer Res. 2017 Aug

15;77(16):4472-4485. doi: 10.1158/0008-5472.CAN-16-2501. Epub 2017 Jun 15. PubMed

PMID: 28619710.


  1. Lopci E, Toschi L, Grizzi F, Rahal D, Olivari L, Castino GF, Marchetti S, Cortese N, Qehajaj D, Pistillo D, Alloisio M, Roncalli M, Allavena P, Santoro A, Marchesi F*, Chiti A*. Correlation of metabolic information on FDG-PET with tissue expression of immune markers in patients with non-small lung cancer (NSCLC) who are candidates for upfront surgery. Eur Nucl Med Mol Imaging 2016; 43 (11): 1954-1961** co-corresponding


7: Liguori M, Buracchi C, Pasqualini F, Bergomas F, Pesce S, Sironi M, Grizzi F,

Mantovani A, Belgiovine C, Allavena P. Functional TRAIL receptors in monocytes

and tumor-associated macrophages: A possible targeting pathway in the tumor

microenvironment. Oncotarget. 2016 Jul 5;7(27):41662-41676. doi:

10.18632/oncotarget.9340. PubMed PMID: 27191500; PubMed Central PMCID:



8:Di Caro G, Cortese N, Castino GF, Grizzi F, Gavazzi F, Ridolfi C, Capretti G, Zerbi A, Allavena P, Mantovani A, Marchesi F. Dual prognostic significance of tumor associated macrophages in patients treated or not with chemotherapy. Gut 2016; 65(10): 1710-1720.


9: Erreni M, Siddiqui I, Marelli G, Grizzi F, Bianchi P, Morone D, Marchesi F,

Celesti G, Pesce S, Doni A, Rumio C, Roncalli MG, Laghi L, Mantovani A, Allavena

  1. The Fractalkine-Receptor Axis Improves Human Colorectal Cancer Prognosis by

Limiting Tumor Metastatic Dissemination. J Immunol. 2016 Jan 15;196(2):902-14.

doi: 10.4049/jimmunol.1501335. Epub 2015 Dec 16. PubMed PMID: 26673138.



10: Mantovani A, Allavena P. The interaction of anticancer therapies with

tumor-associated macrophages. J Exp Med. 2015 Apr 6;212(4):435-45. doi:

10.1084/jem.20150295. Epub 2015 Mar 9. Review. PubMed PMID: 25753580; PubMed

Central PMCID: PMC4387285.


11: Castino GF, Cortese N, Capretti G, Serio S, Di Caro G, Mineri R, Magrini E, Grizzi F, Cappello P, Novelli F, Ridolfi C, Gavazzi F, Zerbi A, Allavena P, Marchesi F. Spatial distribution of B cells predicts prognosis in human pancreatic adenocarcinoma. Oncoimmunology 2015; 5(4):e108514.


12: D’Incalci M, Badri N, Galmarini CM, Allavena P. Trabectedin, a drug acting on

both cancer cells and the tumour microenvironment. Br J Cancer. 2014 Aug

12;111(4):646-50. doi: 10.1038/bjc.2014.149. Epub 2014 Apr 22. Review. PubMed

PMID: 24755886; PubMed Central PMCID: PMC4134488.


13: Mantovani A, Marchesi F. IL-10 and macrophages orchestrate gut homeostasis. Immunity 2014; 40: 637-639.


14: Di Caro G, Marchesi F. Tertiary lymphoid tissue: a gateway for T cells in the tumor microenvironment. Oncoimmunology 2014; 3: e28850.


15: Di Caro G, Bergomas F, Grizzi F, Doni A, Bianchi P, Malesci A, Laghi L, Allavena P, Mantovani A, Marchesi F. Occurrence of tertiary lymphoid tissue is associated to T cell infiltration and predicts better prognosis in early stage colo-rectal cancer. Clinical Cancer Research 2014; 20: 2147-2158


16: Germano G, Frapolli R, Belgiovine C, Anselmo A, Pesce S, Liguori M, Erba E,Uboldi S, Zucchetti M, Pasqualini F, Nebuloni M, van Rooijen N, Mortarini R,Beltrame L, Marchini S, Fuso Nerini I, Sanfilippo R, Casali PG, Pilotti S,Galmarini CM, Anichini A, Mantovani A, D’Incalci M, Allavena P. Role ofmacrophage targeting in the antitumor activity of trabectedin. Cancer Cell. 2013 Feb 11;23(2):249-62. doi: 10.1016/j.ccr.2013.01.008.


17: Solinas G, Schiarea S, Liguori M, Fabbri M, Pesce S, Zammataro L, Pasqualini F, Nebuloni M, Chiabrando C, Mantovani A, Allavena P. Tumor-conditioned macrophages secrete migration-stimulating factor: a new marker for M2-polarization, influencing tumor cell motility. J Immunol. 2010 Jul 1;185(1):642-52.


18: Germano G, Frapolli R, Simone M, Tavecchio M, Erba E, Pesce S, Pasqualini F, Grosso F, Sanfilippo R, Casali PG, Gronchi A, Virdis E, Tarantino E, Pilotti S, Greco A, Nebuloni M, Galmarini CM, Tercero JC, Mantovani A, D’Incalci M, Allavena P. Antitumor and anti-inflammatory effects of trabectedin on human myxoid liposarcoma cells. Cancer Res. 2010 Mar 15;70(6):2235-44.

19: Marchesi F, Martin AP, Thirunarayanan, N, Devany E, Mayer L, Grisotto MG, Furtado GC, Lira SA. CXCL13 expression in the gut promotes accumulation of IL-22-producing lymphoid tissue-inducer cells, and formation of isolated lymphoid follicles. Mucosal Immunology 2009; 2(6): 486-494.



  1. Marchesi F, Piemonti L, Fedele G, Destro A, Roncalli M, Albarello L, Doglioni C, Anselmo A, Doni A, Bianchi P, Laghi L, Malesci A, Cervo L, Malosio ML, Reni M, Zerbi A, Di Carlo V, Mantovani A and Allavena P.. The chemokine receptor CX3CR1 is involved in the neural tropism and malignant behavior of ductal pancreatic adenocarcinoma. Cancer Research 2008: 68: 21.


21: Mantovani A, Allavena P, Sica A, Balkwill F. Cancer-related inflammation. Nature. 2008 Jul 24;454(7203):436-44.