Marianna Paulis Publications - Humanitas Research

Salvarani N., Crasto S., Miragoli M., Bertero A., Paulis M., Kunderfranco P., Serio S., Forni A., Lucarelli C., Dal Ferro M., Larcher V., Sinagra G., Vezzoni P., Murry C.E., Faggian G., Condorelli G., Di Pasquale E. The K219T-Lamin mutation induces conduction defects through epigenetic inhibition of SCN5A in human cardiac laminopathy. Nat Commun. 2019, 10(1):2267. doi: 10.1038/s41467-019-09929-w.
Castelli A., Susani L., Menale C., Muggeo S., Caldana E., Strina D., Cassani B., Recordati C., Scanziani E., Ficara F., Villa A., Vezzoni P., Paulis M. Chromosome Transplantation: Correction of the Chronic Granulomatous Disease Defect in Mouse Induced Pluripotent Stem Cells. Stem Cells. 2019 Mar 20. doi: 10.1002/stem.3006.
Crociara P., Chieppa M.N., Costassa E.V., Berrone E., Gallo M., Faro M.L., Pintore M.D., Iulini B., D’Angelo A., Perona G., Botter A., Formicola D., Rainoldi A., Paulis M., Vezzoni P., Meli F., Peverali F.A., Bendotti C., Trolese M.C., Pasetto L., Bonetto V., Lazzari G., Duchi R., Perota A., Lagutina I., Quadalti C., Gennero M.S., Dezzutto D., Desiato R., Boido M., Ghibaudi M., Valentini M.C., Caramelli M., Galli C., Casalone C., Corona C. Motor neuron degeneration, severe myopathy and TDP-43 increase in a transgenic pig model of SOD1-linked familiar ALS. Neurobiol Dis. 2018, S0969-9961(18)30752-6. doi: 10.1016/j.nbd.2018.11.021
Susani L., Castelli A., Lizier M., Lucchini F., Vezzoni P., Paulis M. Correction of a Recessive Genetic Defect by CRISPR-Cas9-Mediated Endogenous Repair. The CRISPR Journal; 2018, 1(3):230-238. PMID: 28191778
Meneghini V., Frati G., Sala D., De Cicco S., Luciani M., Cavazzin C., Paulis M., Mentzen W., Morena F., Giannelli S., Sanvito F., Villa A., Bulfone A., Broccoli V., Martino S., Gritti A. Generation of Human Induced Pluripotent Stem Cell‐Derived Bona Fide Neural Stem Cells for Ex Vivo Gene Therapy of Metachromatic Leukodystrophy. Stem Cells Translational Medicine; 2017, 6:352–368. doi.org/10.5966/sctm.2015-0414
Lizier M., Anselmo A., Mantero S., Ficara F., Paulis M., Vezzoni P., Lucchini F., and Pacchiana G. Fusion between cancer cells and macrophages occurs in a murine model of spontaneous neu+ breast cancer without increasing its metastatic potential. Oncotarget; 2016, 7(38): 60793–60806. doi: 18632/oncotarget.11508
Paulis M., Castelli A., Susani L., Lizier M., Lagutina I., Focarelli M.L., Recordati C., Uva P., Faggioli F., Neri T., Scanziani E., Galli C., Lucchini F., Villa A., Vezzoni P. Chromosome transplantation as a novel approach for correcting complex genomic disorders. Oncotarget; 2015, 6(34):35218-30. doi: 10.18632/oncotarget.6143.
Neri T., Muggeo S., Paulis M., Caldana M.E., Crisafulli L., Strina D., Focarelli M.L., Faggioli F., Recordati C., Scaramuzza S., Scanziani E., Mantero S., Buracchi C., Sobacchi C., Lombardo A, Naldini L, Vezzoni P, Villa A, Ficara F. Targeted Gene Correction in Osteopetrotic-Induced Pluripotent Stem Cells for the Generation of Functional Osteoclasts. Stem Cell Reports; 2015, 5(4):558-68. doi:10.1016/j.stemcr.2015.08.005.
Paulis M., Castelli A., Lizier M., Susani L., Lucchini F., Villa A., Vezzoni P. A pre-screening FISH-based method to detect CRISPR/Cas9 off-targets in mouse embryonic stem cells. Sci Rep; 2015, 5:12327. doi: 10.1038/srep12327.
Santin G., Paulis M., Vezzoni P., Pacchiana G., Bottiroli G., Croce A.C. Autofluorescence properties of murine embryonic stem cells during spontaneous differentiation phases. Lasers Surg Med; 2013, 45(9):597-607. doi: 10.1002/lsm.22182.
Lo Iacono N., Blair H.C., Poliani P.L., Marrella V., Ficara F., Cassani B., Facchetti F., Fontana E., Guerrini M.M., Traggiai E., Schena F., Paulis M., Mantero S., Inforzato A., Valaperta S., Pangrazio A., Crisafulli L., Maina V., Kostenuik P., Vezzoni P., Villa A., Sobacchi C. Osteopetrosis rescue upon RANKL administration to Rankl(-/-) mice: a new therapy for human RANKL-dependent ARO. J Bone Miner Res; 2012, 27(12):2501-10. doi: 10.1002/jbmr.1712.
Marrella V., Poliani P.L., Fontana E., Casati A., Maina V., Cassani B., Ficara F., Cominelli M., Schena F., Paulis M., Traggiai E., Vezzoni P., Grassi F., Villa A. Anti-CD3ε mAb improves thymic architecture and prevents autoimmune manifestations in a mouse model of Omenn syndrome: therapeutic implications. Blood; 2012, 120(5):1005-14. doi: 10.1182/blood-2012-01-406827.
Paulis M. Chromosome transfer via cell fusion. Methods Mol Biol; 2011, 738:57-67.
Revenkova E, Focarelli ML, Susani L, Paulis M., Bassi MT, Mannini L, Frattini A, Delia D, Krantz I, Vezzoni P, Jessberger R, Musio. Cornelia de Lange syndrome mutations in SMC1A or SMC3 affect binding to DNA. Hum Mol Genet; 2009, 18(3):418-27.
Focarelli ML, Soza S, Mannini L, Paulis M., Montecucco A, Musio A. Claspin inhibition leads to fragile site expression. Genes Chromosomes Cancer; 2009, 48(12):1083-90.
Paulis M, Bensi M, Orioli D, Mondello C, Mazzini G, D’Incalci M, Falcioni C, Radaelli E, Erba E, Raimondi E, De Carli L. Transfer of a human chromosomal vector from a hamster cell line to a mouse embryonic stem cell line. Stem Cells; 2007, 25(10):2543-50.
Uboldi C., Paulis M., Guidi E., Bertoni A., Meo G.P., Perucatti A., Iannuzzi L., Raimondi E., Brunner R.M., Eggen A., Ferretti L. Cloning of the bovine prion-like Shadoo (SPRN) gene by comparative analysis of the predicted genomic locus. Mamm Genome; 2006, 17(11):1130-9.
Paulis M., Bensi M., Moralli D., De Carli L. and Raimondi E. A Set of Duplicons on Human Chromosome 9 is Involved in the Origin of a Supernumerary Marker Chromosome. Genomics; 2006, 87(6):747-757.
Uboldi C., Del Vecchio I., Foti M.G., Azzalin A., Paulis M., Raimondi E., Vaccari G., Agrimi U., Di Guardo G., Comincini S., Ferretti L. Prion-like Doppel gene (PRND) in the goat: genomic structure, cDNA and polymorphisms. Mammalian Genome; 2005, 16: 963-971.
Paulis M., Moralli D., Bensi M., De Carli L. and Raimondi E. Isolation from the horse genome of a new DNA transposon belonging to the Tigger Mammalian Genome; 2004, 15(5): 399-403.