2021:

Serum Amyloid P component is an essential element of resistance against Aspergillus fumigatus.

Doni A, Parente R, Laface I, Magrini E, Cunha C, Colombo FS, Lacerda JF, Campos Jr A, Mapelli SN, Petroni F, Porte R, Schorn T, Inforzato A, Mercier T, Lagrou K, Maertens J, Lambris JD, Bottazzi B, Garlanda C, Botto M, Carvalho A, Mantovani A.

Nature Communications 2021 Jun 18,12(1):3739. doi: 10.1038/s41467-021-24021-y.

 

Nanoscale study of calcium handling remodeling in right ventricular cardiomyocytes following pulmonary hypertension.

Medvedev R, Sanchez-Alonso JL, Alvarez-Laviada A, Rossi S, Dries E, Schorn T, Abdul-Salam VB, Trayanova N, Wojciak-Stothard B, Miragoli M, Faggian G, Gorelik J.

Hypertension 2021 Feb;77(2): 605-616. doi: 10.1161/HYPERTENSIONAHA.120.14858.

 

 

2020:

Nanobodies as Versatile Tool for Multiscale Imaging Modalities.

Erreni M, Schorn T, D’Autilia F, Doni A.

Biomolecules  2020 Dec 18;10(12): 1695. doi: 10.3390/biom10121695.

 

Local externalization of phosphatidylserine mediates developmental synaptic pruning by microglia.

Scott-Hewitt N, Perrucci F, Morini R, Erreni M, Mahoney M, Witkowska A, Carey A, Faggiani E, Schuetz LT, Mason S, Tamborini M, Bizzotto M, Passoni L, Filipello F, Jahn R, Stevens B, Matteoli M.

EMBO J. 2020 Aug 17;39(16):e105380. doi: 10.15252/embj.2020105380.

 

Optimization of a Luciferase-Expressing Non-Invasive Intrapleural Model of Malignant Mesothelioma in Immunocompetent Mice.

Digifico E, Erreni M, Colombo FS, Recordati C, Migliore R, Frapolli R, D’Incalci M, Belgiovine C, Allavena P.

Cancer (Basel). 2020 Aug 1;12(8):2136. doi: 10.3390/cancers12082136.

 

The complement system in Aspergillus fumigatus infections and its crosstalk with pentraxins.

Parente R, Doni A, Bottazzi B, Garlanda C, Inforzato A.

FEBS Lett. 2020 Aug;594(16):2480-2501. doi: 10.1002/1873-3468.13744.

 

Intestinal Macrophages at the Crossroad between Diet, Inflammation, and Cancer.

Caprara G, Allavena P, Erreni M.

Int J Mol Sci. 2020 Jul 8;21(14):4825. doi: 10.3390/ijms21144825.

 

Tumor-Derived Prostaglandin E2 Promotes p50 NF-κB-Dependent Differentiation of Monocytic MDSCs.

Porta C, Consonni FM, Morlacchi S, Sangaletti S, Bleve A, Totaro MG, Larghi P, Rimoldi M, Tripodo C, Strauss L, Banfi S, Storto M, Pressiani T, Rimassa L, Tartari S, Ippolito A, Doni A, Soldà G, Duga S, Piccolo V, Ostuni R, Natoli G, Bronte V, Balzac F, Turco E, Hirsch E, Colombo MP, Sica A.

Cancer Res. 2020 Jul 1;80(13):2874-2888. doi: 10.1158/0008-5472.CAN-19-2843.

 

Evaluation of cell metabolic adaptation in wound and tumor by Fluorescence Lifetime Imaging Microscopy.

Morone D, D’Autilia F, Schorn T, Erreni M, Doni A.

Sci Rep. 2020 Apr 14;10(1):6289. doi: 10.1038/s41598-020-63203-4.

 

Metabolome of Pancreatic Juice Delineates Distinct Clinical Profiles of Pancreatic Cancer and Reveals a Link between Glucose Metabolism and PD-1 + Cells.

Cortese N, Capretti G, Barbagallo M, Rigamonti A, Takis PG, Castino GF, Vignali D, Maggi G, Gavazzi F, Ridolfi C, Nappo G, Donisi G, Erreni M, Avigni R, Rahal D, Spaggiari P, Roncalli M, Cappello P, Novelli F, Monti P, Zerbi A, Allavena P, Mantovani A, Marchesi F.

Cancer Immunol Res. 2020 Apr;8(4):493-505. doi: 10.1158/2326-6066.CIR-19-0403.

 

 

2019:

Single Cell Sequencing of Mouse Heart Immune Infiltrate in Pressure Overload-Driven Heart Failure Reveals Extent of Immune Activation.

Martini E, Kunderfranco P, Peano C, Carullo P, Cremonesi M, Schorn T, Carriero R, Termanini A, Colombo FS, Jachetti E, Panico C, Faggian G, Fumero A, Torracca L, Molgora M, Cibella J, Pagiatakis C, Brummelman J, Alvisi G, Mazza EMC, Colombo MP, Lugli E, Condorelli G, Kallikourdis M.

Circulation. 2019 Dec 17;140(25):2089-2107. doi: 10.1161/CIRCULATIONAHA.119.041694.

 

The macrophage tetraspan MS4A4A enhances dectin-1-dependent NK cell-mediated resistance to metastasis.

Mattiola I, Tomay F, De Pizzol M, Silva-Gomes R, Savino B, Gulic T, Doni A, Lonardi S, Astrid Boutet M, Nerviani A, Carriero R, Molgora M, Stravalaci M, Morone D, Shalova IN, Lee Y, Biswas SK, Mantovani G, Sironi M, Pitzalis C, Vermi W, Bottazzi B, Mantovani A, Locati M.

Nat Immunol. 2019 Jul 1. doi: 10.1038/s41590-019-0417-y. [Epub ahead of print]

 

TNF-Stimulated Gene-6 Is a Key Regulator in Switching Stemness and Biological Properties of Mesenchymal Stem Cells.

Romano B, Elangovan S, Erreni M, Sala E, Petti L, Kunderfranco P, Massimino L, Restelli S, Sinha S, Lucchetti D, Anselmo A, Colombo FS, Stravalaci M, Arena V, D’Alessio S, Ungaro F, Inforzato A, Izzo AA, Sgambato A, Day AJ, Vetrano S.

Stem Cells. 2019 Apr 3. doi: 10.1002/stem.3010. [Epub ahead of print]

 

Circ_Lrp6, a Circular RNA Enriched in Vascular Smooth Muscle Cells, Acts as a Sponge Regulating miRNA-145 Function.

Hall IF, Climent M, Quintavalle M, Farina FM, Schorn T, Zani S, Carullo P, Kunderfranco P, Civilini E, Condorelli G, Elia L.

Circ Res. 2019 Feb 15;124(4):498-510. doi: 10.1161/CIRCRESAHA.118.314240.

 

Macrophage ferroportin is essential for stromal cell proliferation in wound healing.

Recalcati S, Gammella E, Buratti P, Doni A, Anselmo A, Locati M, Cairo G.

Haematologica. 2019 Jan;104(1):47-58. doi: 10.3324/haematol.2018.197517. Epub 2018 Aug 16.

 

 

 2018: 

3D Bone Biomimetic Scaffolds for Basic and Translational Studies with Mesenchymal Stem Cells.

Sobacchi C, Erreni M, Strina D, Palagano E, Villa A, Menale C.

Int J Mol Sci. 2018 Oct 13;19(10). pii: E3150. doi: 10.3390/ijms19103150. Review.

 

MSC-Seeded Biomimetic Scaffolds as a Factory of Soluble RANKL in Rankl-Deficient Osteopetrosis.

Menale C, Campodoni E, Palagano E, Mantero S, Erreni M, Inforzato A, Fontana E, Schena F, Van’t Hof R, Sandri M, Tampieri A, Villa A, Sobacchi C.

Stem Cells Transl Med. 2018 Sep 5. doi: 10.1002/sctm.18-0085.

 

Optical in vivo imaging detection of preclinical models of gut tumors through the expression of integrin αVβ3.

Marelli G, Avigni R, Allavena P, Garlanda C, Mantovani A, Doni A, Erreni M.

Oncotarget. 2018 Jul 31;9(59):31380-31396. doi: 10.18632/oncotarget.25826. eCollection 2018 Jul 31.

 

The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity.

Filipello F, Morini R, Corradini I, Zerbi V, Canzi A, Michalski B, Erreni M, Markicevic M, Starvaggi-Cucuzza C, Otero K, Piccio L, Cignarella F, Perrucci F, Tamborini M, Genua M, Rajendran L, Menna E, Vetrano S, Fahnestock M, Paolicelli RC, Matteoli M.

Immunity. 2018 May 15;48(5):979-991.e8. doi: 10.1016/j.immuni.2018.04.016. Epub 2018 May 8.

 

Maternal Immune Activation Delays Excitatory-to-Inhibitory Gamma-Aminobutyric Acid Switch in Offspring.

Corradini I, Focchi E, Rasile M, Morini R, Desiato G, Tomasoni R, Lizier M, Ghirardini E, Fesce R, Morone D, Barajon I, Antonucci F, Pozzi D, Matteoli M.

Biol Psychiatry. 2018 Apr 15;83(8):680-691. doi: 10.1016/j.biopsych.2017.09.030. Epub 2017 Nov 14

 

Inhalation of peptide-loaded nanoparticles improves heart failure.

Miragoli M, Ceriotti P, Iafisco M, Vacchiano M, Salvarani N, Alogna A, Carullo P, Ramirez-Rodríguez GB, Patrício T, Esposti LD, Rossi F, Ravanetti F, Pinelli S, Alinovi R, Erreni M, Rossi S, Condorelli G, Post H, Tampieri A, Catalucci D.

Sci Transl Med. 2018 Jan 17;10(424). pii: eaan6205. doi: 10.1126/scitranslmed.aan6205.

 

An autofluorescence-based method for the isolation of highly purified ventricular cardiomyocytes.

Larcher V, Kunderfranco P, Vacchiano M, Carullo P, Erreni M, Salamon I, Colombo FS, Lugli E, Mazzola M, Anselmo A, Condorelli G.

Cardiovasc Res. 2018 Mar 1;114(3):409-416. doi: 10.1093/cvr/cvx239.

 

 

2017:

IL-1R8 is a checkpoint in NK cells regulating anti-tumour and anti-viral activity.

Molgora M, Bonavita E, Ponzetta A, Riva F, Barbagallo M, Jaillon S, Popović B, Bernardini G, Magrini E, Gianni F, Zelenay S, Jonjić S, Santoni A, Garlanda C, Mantovani A.

Nature. 2017 Nov 2;551(7678):110-114. doi: 10.1038/nature24293. Epub 2017 Oct 25.

 

Identification of human somatostatin receptor 2 domains involved in internalization and signaling in QGP-1 pancreatic neuroendocrine tumor cell line.

Cambiaghi V, Vitali E, Morone D, Peverelli E, Spada A, Mantovani G, Lania AG.

Endocrine. 2017 Apr;56(1):146-157. doi: 10.1007/s12020-016-1026-2. Epub 2016 Jul 12.

 

 

 

 

 

2016:

Adeno-associated virus-mediated CASQ2 delivery rescues phenotypic alterations in a patient-specific model of recessive catecholaminergic polymorphic ventricular tachycardia.

Lodola F, Morone D, Denegri M, Bongianino R, Nakahama H, Rutigliano L, Gosetti R, Rizzo G, Vollero A, Buonocore M, Napolitano C, Condorelli G, Priori SG, Di Pasquale E.

Cell Death Dis. 2016 Oct 6;7(10):e2393. doi: 10.1038/cddis.2016.304.

 

Tailored chemokine receptor modification improves homing of adoptive therapy T cells in a spontaneous tumor model.

Garetto S, Sardi C, Martini E, Roselli G, Morone D, Angioni R, Cianciotti BC, Trovato AE, Franchina DG, Castino GF, Vignali D, Erreni M, Marchesi F, Rumio C, Kallikourdis M.

Oncotarget. 2016 Jul 12;7(28):43010-43026. doi: 10.18632/oncotarget.9280.

 

The Fractalkine-Receptor Axis Improves Human Colorectal Cancer Prognosis by Limiting Tumor Metastatic Dissemination.

Erreni M, Siddiqui I, Marelli G, Grizzi F, Bianchi P, Morone D, Marchesi F, Celesti G, Pesce S, Doni A, Rumio C, Roncalli MG, Laghi L, Mantovani A, Allavena P.

J Immunol. 2016 Jan 15;196(2):902-14. doi: 10.4049/jimmunol.1501335. Epub 2015 Dec 16.

 

 

2015:

 

RORC1 Regulates Tumor-Promoting “Emergency” Granulo-Monocytopoiesis.

Strauss L, Sangaletti S, Consonni FM, Szebeni G, Morlacchi S, Totaro MG, Porta C, Anselmo A, Tartari S, Doni A, Zitelli F, Tripodo C, Colombo MP, Sica A.

Cancer Cell. 2015 Aug 10;28(2):253-69. doi: 10.1016/j.ccell.2015.07.006

 

An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair mode.

Doni A, Musso T, Morone D, Bastone A, Zambelli V, Sironi M, Castagnoli C, Cambieri I, Stravalaci M, Pasqualini F, Laface I, Valentino S, Tartari S, Ponzetta A, Maina V, Barbieri SS, Tremoli E, Catapano AL, Norata GD, Bottazzi B, Garlanda C, Mantovani A.

J Exp Med. 2015 Jun 1;212(6):905-25. doi: 10.1084/jem.20141268. Epub 2015 May 11.

 

 

2014:

 

Endothelial deficiency of L1 reduces tumor angiogenesis and promotes vessel normalization.

Magrini E, Villa A, Angiolini F, Doni A, Mazzarol G, Rudini N, Maddaluno L, Komuta M, Topal B, Prenen H, Schachner M, Confalonieri S, Dejana E, Bianchi F, Mazzone M, Cavallaro U.

J Clin Invest. 2014 Oct;124(10):4335-50. doi: 10.1172/JCI70683. Epub 2014 Aug 26.

 

Occurrence of tertiary lymphoid tissue is associated with T-cell infiltration and predicts better prognosis in early-stage colorectal cancers.

Di Caro G, Bergomas F, Grizzi F, Doni A, Bianchi P, Malesci A, Laghi L, Allavena P, Mantovani A, Marchesi F.

Clin Cancer Res. 2014 Apr 15;20(8):2147-58. doi: 10.1158/1078-0432.CCR-13-2590. Epub 2014 Feb 12.

 

 

2010:

Human glioblastoma tumours and neural cancer stem cells express the chemokine CX3CL1 and its receptor CX3CR1.

Erreni M, Solinas G, Brescia P, Osti D, Zunino F, Colombo P, Destro A, Roncalli M, Mantovani A, Draghi R, Levi D, Rodriguez Y Baena R, Gaetani P, Pelicci G, Allavena P.

Eur J Cancer. 2010 Dec;46(18):3383-92. doi: 10.1016/j.ejca.2010.07.022. Epub 2010 Aug 19.

 

Role of complement and Fc{gamma} receptors in the protective activity of the long pentraxin PTX3 against Aspergillus fumigatus.

Moalli F, Doni A, Deban L, Zelante T, Zagarella S, Bottazzi B, Romani L, Mantovani A, Garlanda C.

Blood. 2010 Dec 9;116(24):5170-80. doi: 10.1182/blood-2009-12-258376. Epub 2010 Sep 9.

 

 

 

2007:

 

The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localizes in extracellular traps.

Jaillon S, Peri G, Delneste Y, Frémaux I, Doni A, Moalli F, Garlanda C, Romani L, Gascan H, Bellocchio S, Bozza S, Cassatella MA, Jeannin P, Mantovani A.

J Exp Med. 2007 Apr 16;204(4):793-804. Epub 2007 Mar 26.