Selected Publications: 20-25 publications listed in details with all the contributing authors, title of the papers, journal, dates.

 

1: Mattiola I, Tomay F, De Pizzol M, Silva-Gomes R, Savino B, Gulic T, Doni A, Lonardi S, Astrid Boutet M, Nerviani A, Carriero R, Molgora M, Stravalaci M, Morone D, Shalova IN, Lee Y, Biswas SK, Mantovani G, Sironi M, Pitzalis C, Vermi W, Bottazzi B, Mantovani A, Locati M. The macrophage tetraspan MS4A4A enhances dectin-1-dependent NK cell-mediated resistance to metastasis. Nat Immunol. 2019 Aug;20(8):1012-1022. doi: 10.1038/s41590-019-0417-y.  https://www.ncbi.nlm.nih.gov/pubmed/31263276

 

2: Del Prete A, Sozio F, Schioppa T, Ponzetta A, Vermi W, Calza S, Bugatti M, Salvi V, Bernardini G, Benvenuti F, Vecchi A, Bottazzi B, Mantovani A, Sozzani S. The Atypical Receptor CCRL2 Is Essential for Lung Cancer Immune Surveillance. Cancer Immunol Res. 2019 Nov;7(11):1775-1788. doi: 10.1158/2326-6066.CIR-19-0168. Epub 2019 Sep 4. PubMed PMID: 31484658. https://www.ncbi.nlm.nih.gov/pubmed/31484658

 

3: Bottazzi B, Riboli E, Mantovani A. Aging, inflammation and cancer. Semin Immunol. 2018 Nov 5. pii: S1044-5323(18)30082-4. doi: 10.1016/j.smim.2018.10.011. [Epub ahead of print] https://www.ncbi.nlm.nih.gov/pubmed/30409538

 

4: Fossati G, Pozzi D, Canzi A, Mirabella F, Valentino S, Morini R, Ghirardini E, Filipello F, Moretti M, Gotti C, Annis DS, Mosher DF, Garlanda C, Bottazzi B, Taraboletti G, Mantovani A, Matteoli M, Menna E. Pentraxin 3 regulates synaptic function by inducing AMPA receptor clustering via ECM remodeling and β1-integrin. EMBO J. 2018 Nov 5. pii: e99529. doi: 10.15252/embj.201899529. [Epub ahead of print] https://www.ncbi.nlm.nih.gov/pubmed/30396995

 

5: Grčević D, Sironi M, Valentino S, Deban L, Cvija H, Inforzato A, Kovačić N, Katavić V, Kelava T, Kalajzić I, Mantovani A, Bottazzi B. The Long Pentraxin 3 Plays a Role in Bone Turnover and Repair. Front Immunol. 2018 Mar 5;9:417. doi: 10.3389/fimmu.2018.00417. eCollection 2018. https://www.ncbi.nlm.nih.gov/pubmed/29556234

 

6: Garlanda C, Bottazzi B, Magrini E, Inforzato A, Mantovani A. PTX3, a Humoral Pattern Recognition Molecule, in Innate Immunity, Tissue Repair, and Cancer. Physiol Rev. 2018 Apr 1;98(2):623-639. doi: 10.1152/physrev.00016.2017. https://www.ncbi.nlm.nih.gov/pubmed/29412047

 

7: Lussana F, Carobbio A, Salmoiraghi S, Guglielmelli P, Vannucchi AM, Bottazzi B, Leone R, Mantovani A, Barbui T, Rambaldi A. Driver mutations (JAK2V617F, MPLW515L/K or CALR), pentraxin-3 and C-reactive protein in essential thrombocythemia and polycythemia vera. J Hematol Oncol. 2017 Feb 22;10(1):54. doi: 10.1186/s13045-017-0425-z. https://www.ncbi.nlm.nih.gov/pubmed/28228104

 

8: Dander E, De Lorenzo P, Bottazzi B, Quarello P, Vinci P, Balduzzi A, Masciocchi F, Bonanomi S, Cappuzzello C, Prunotto G, Pavan F, Pasqualini F, Sironi M, Cuccovillo I, Leone R, Salvatori G, Parma M, Terruzzi E, Pagni F, Locatelli F, Mantovani A, Fagioli F, Biondi A, Garlanda C, Valsecchi MG, Rovelli A, D’Amico G. Pentraxin 3 plasma levels at graft-versus-host disease onset predict disease severity and response to therapy in children given haematopoietic stem cell transplantation. Oncotarget. 2016 Dec 13;7(50):82123-82138. doi: 10.18632/oncotarget.13488. https://www.ncbi.nlm.nih.gov/pubmed/27893415

 

9: Caironi P, Masson S, Mauri T, Bottazzi B, Leone R, Magnoli M, Barlera S, Mamprin F, Fedele A, Mantovani A, Tognoni G, Pesenti A, Gattinoni L, Latini R; ALBIOS Biomarkers Study Investigators. Pentraxin 3 in patients with severe sepsis or shock: the ALBIOS trial. Eur J Clin Invest. 2017 Jan;47(1):73-83. doi: 10.1111/eci.12704. https://www.ncbi.nlm.nih.gov/pubmed/27864924

 

10: Doni A, Musso T, Morone D, Bastone A, Zambelli V, Sironi M, Castagnoli C, Cambieri I, Stravalaci M, Pasqualini F, Laface I, Valentino S, Tartari S, Ponzetta A, Maina V, Barbieri SS, Tremoli E, Catapano AL, Norata GD, Bottazzi B, Garlanda C, Mantovani A. An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair mode. J Exp Med. 2015 Jun 1;212(6):905-25. doi: 10.1084/jem.20141268. https://www.ncbi.nlm.nih.gov/pubmed/25964372

 

11: Bottazzi B, Santini L, Savino S, Giuliani MM, Dueñas Díez AI, Mancuso G, Beninati C, Sironi M, Valentino S, Deban L, Garlanda C, Teti G, Pizza M, Rappuoli R, Mantovani A. Recognition of Neisseria meningitidis by the long pentraxin PTX3 and its role as an endogenous adjuvant. PLoS One. 2015 Mar 18;10(3):e0120807. doi: 10.1371/journal.pone.0120807. https://www.ncbi.nlm.nih.gov/pubmed/25786110

 

12: Latini R, Gullestad L, Masson S, Nymo SH, Ueland T, Cuccovillo I, Vårdal M, Bottazzi B, Mantovani A, Lucci D, Masuda N, Sudo Y, Wikstrand J, Tognoni G, Aukrust P, Tavazzi L; Investigators of the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA) and GISSI-Heart Failure (GISSI-HF) trials. Pentraxin-3 in chronic heart failure: the CORONA and GISSI-HF trials. Eur J Heart Fail. 2012 Sep;14(9):992-9. https://www.ncbi.nlm.nih.gov/pubmed/22740508

 

13: Deban L, Russo RC, Sironi M, Moalli F, Scanziani M, Zambelli V, Cuccovillo I, Bastone A, Gobbi M, Valentino S, Doni A, Garlanda C, Danese S, Salvatori G, Sassano M, Evangelista V, Rossi B, Zenaro E, Constantin G, Laudanna C, Bottazzi B, Mantovani A. Regulation of leukocyte recruitment by the long pentraxin PTX3. Nat Immunol. 2010 Apr;11(4):328-34. doi: 10.1038/ni.1854. https://www.ncbi.nlm.nih.gov/pubmed/20208538

 

14: Bottazzi B, Doni A, Garlanda C, Mantovani A. An integrated view of humoral innate immunity: pentraxins as a paradigm. Annu Rev Immunol. 2010;28:157-83. doi: 10.1146/annurev-immunol-030409-101305. Review. https://www.ncbi.nlm.nih.gov/pubmed/19968561

 

15: Inforzato A, Baldock C, Jowitt TA, Holmes DF, Lindstedt R, Marcellini M, Rivieccio V, Briggs DC, Kadler KE, Verdoliva A, Bottazzi B, Mantovani A, Salvatori G, Day AJ. The angiogenic inhibitor long pentraxin PTX3 forms an asymmetric octamer with two binding sites for FGF2. J Biol Chem. 2010 Jun 4;285(23):17681-92. doi: 10.1074/jbc.M109.085639. https://www.ncbi.nlm.nih.gov/pubmed/20363749

 

16: Jeannin P, Bottazzi B, Sironi M, Doni A, Rusnati M, Presta M, Maina V, Magistrelli G, Haeuw JF, Hoeffel G, Thieblemont N, Corvaia N, Garlanda C, Delneste Y, Mantovani A. Complexity and complementarity of outer membrane protein A recognition by cellular and humoral innate immunity receptors. Immunity. 2005 May;22(5):551-60. https://www.ncbi.nlm.nih.gov/pubmed/15894273

 

17: Garlanda C, Bottazzi B, Bastone A, Mantovani A. Pentraxins at the crossroads between innate immunity, inflammation, matrix deposition, and female fertility. Annu Rev Immunol. 2005;23:337-66. https://www.ncbi.nlm.nih.gov/pubmed/15771574

 

18: Bottazzi B, Vouret-Craviari V, Bastone A, De Gioia L, Matteucci C, Peri G, Spreafico F, Pausa M, D’Ettorre C, Gianazza E, Tagliabue A, Salmona M, Tedesco F, Introna M, Mantovani A. Multimer formation and ligand recognition by the long pentraxin PTX3. Similarities and differences with the short pentraxins C-reactive protein and serum amyloid P component. J Biol Chem. 1997 Dec 26;272(52):32817-23. https://www.ncbi.nlm.nih.gov/pubmed/9407058

 

19: Breviario F, d’Aniello EM, Golay J, Peri G, Bottazzi B, Bairoch A, Saccone S, Marzella R, Predazzi V, Rocchi M, Della Valle G, Dejana E, Mantovani A, Introna M. Interleukin-1-inducible genes inendothelial cells. Cloning of a new gene related to C-reactive protein and serum amyloid P component. J Biol Chem. 1992 Nov 5;267(31):22190-7. https://www.ncbi.nlm.nih.gov/pubmed/1429570

 

20: Mantovani A, Bottazzi B, Colotta F, Sozzani S, Ruco L. The origin and function of tumor-associated macrophages. Immunol Today. 1992 Jul;13(7):265-70. https://www.ncbi.nlm.nih.gov/pubmed/1388654

 

21: Bottazzi B, Erba E, Nobili N, Fazioli F, Rambaldi A, Mantovani A. A paracrine circuit in the regulation of the proliferation of macrophages infiltrating murine sarcomas. J Immunol. 1990 Mar 15;144(6):2409-12. https://www.ncbi.nlm.nih.gov/pubmed/2138198

 

22: Bottazzi B, Polentarutti N, Acero R, Balsari A, Boraschi D, Ghezzi P, Salmona M, Mantovani A. Regulation of the macrophage content of neoplasms by chemoattractants. Science. 1983 Apr 8;220(4593):210-2. https://www.ncbi.nlm.nih.gov/pubmed/6828888